Medical / Clinical Research

A chronic disease characterized by the compulsive use of opioids (e.g., heroin, fentanyl, oxycodone) despite harmful consequences. It affects brain function and behavior.

The process of monitoring, detecting, and assessing adverse effects of medications to ensure drug safety.

A study that includes a group receiving an inactive treatment (placebo) to compare against the active treatment’s effects.

The use of more than one drug or substance, either simultaneously or in close succession. It can be intentional or unintentional and may increase risk for overdose or other harms.

Any change or departure from the planned study procedures, which must be documented and reported.

A study in which participants are randomly assigned to treatment or control groups to evaluate the effectiveness of an intervention.

A meeting conducted before a clinical trial begins at a research site. It ensures that the site staff understand the study protocol, procedures, and responsibilities.

The delivery of healthcare services remotely using communication technology, such as video calls or phone consultations, often used to expand access to care.

A publicly accessible database (e.g., ClinicalTrials.gov) where key details of clinical trials are recorded and shared to promote transparency and accountability.

Any unwanted or harmful outcome experienced by a participant during a clinical study, whether or not it is related to the study intervention.