Opioid Use Disorder [OUD]
A chronic disease characterized by the compulsive use of opioids (e.g., heroin, fentanyl, oxycodone) despite harmful consequences. It affects brain function and behavior.
Intention-to-treat analysis
A method of analysis that includes all participants in the groups to which they were originally assigned, regardless of whether they completed the intervention.
Good Clinical Practice [GCP]
An international set of ethical and scientific standards for designing, conducting, and reporting clinical trials involving human participants.
Comorbidity
The presence of more than one disorder or condition in the same person, either at the same time or over a period of time (e.g., depression and anxiety).
Clinical endpoint
A clearly defined outcome used to determine whether a treatment is effective (e.g., symptom improvement, survival rate).
Case Report Form [CRF]
A standardized document used to collect data from each participant in a clinical trial, often electronically.
Buprenorphine
A medication used to treat opioid use disorder. It reduces cravings and withdrawal symptoms. Brand names include Suboxone, Subutex, Sublocade, and Zubsolv.
Adverse event
Any unwanted or harmful outcome experienced by a participant during a clinical study, whether or not it is related to the study intervention.
Trauma-informed care
An approach to service delivery that recognizes the widespread impact of trauma and integrates this awareness into policies, procedures, and practices.
Transference
A psychological phenomenon in which a person redirects feelings or expectations from one relationship (often from early life) onto a therapist or another figure in the present.
